Category: Journal

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jhc2026v10i2s14

Case Report
Eosinophilic Mastitis: A Rare Case Report
Hussain AR,1 *Khanam KF,2 Akhter S,3 Omar T,4 Ayeeda AS,5  Khanam KA6

  1. Dr. Ahmed Redwan Hussain, Resident, Phase B, Department. of Pathology, Bangladesh Medical University. redwanayon8@gmail.com. https://orcid.org/0009-0007-6173-797X
  2. *Dr. Kazi Farzana Khanam, Assistant Professor, Department of Pathology, Bangladesh Medical University.kazifarzanabmu@gmail.com. Orcid: https://orcid.org/0009-0005-3496-7337
  3. Dr. Shabnam Akhter, Associate Professor, Department of Pathology, Bangladesh Medical University. akhtershabnam66@gmail.com.
  4. Dr. Tasnim Omar, Resident, Phase B, Department of Pathology, Bangladesh Medical University. tasnimomar46@gmail.com. https://orcid.org/0009-0006-4947-3759
  5. Dr. Ayesha Sadia Ayeeda, Resident, Phase B, Department of Pathology, Bangladesh Medical University. Ayeeda.ayesha@gmail.com. https://orcid.org/0009-0002-6709-3582
  6. Dr. Kazi Arhamna Khanam, Resident, Phase B, Department of Obstetrics and Gynaecology, Institute of Child and mother health, Dhaka. arhamna.ilka100@gmail.com. https://orcid.org/0009-0001-7264-0520

*For correspondence

Abstract
Eosinophilic mastitis is a rare benign condition characterized by eosinophilic infiltrate around the duct and lobules of the mammary gland leading to inflammation. Although eosinophilic mastitis is a benign condition, it presents similarly to and is often mistaken for breast cancer. We report the case of a 35 years old female presenting with a short history of mastitis with mild fever and swelling of her left breast. A breast imaging with ultrasonography revealed ill-defined mixed echogenic area in the left breast at 5-7 o’clock position along with features of duct ectasia. Histopathological procedure with core needle biopsy demonstrated inflammatory infiltrate predominantly eosinophils without evidence of malignancy. The patient was diagnosed as eosinophilic mastitis.

[Journal of Histopathology and Cytopathology, 2026 Jul; 10 (2):179-182]
DOI: https://www.doi.org/10.69950/jhc.2026.10.2.14

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jhc2026v10i2s12

Case Report
Pulmonary Sclerosing Pneumocytoma: Diagnostic Challenges in Frozen Section – A Case Report and Literature Review
*Anjum R,1 Hossain Bhuiyan MZ 2

  1. *Dr. Rahat Anjum, Associate Consultant, Histopathology & Cytopathology, Apollo Imperial Hospitals, Zakir Hossain Road, Chittagong. r.dr@gmail.com. https://orcid.org/0009-0005-2233-6992
  2. Dr. Mohammad Zakir Hossain Bhuiyan, Associate Professor, Department of Thoracic Surgery, Chittagong Medical College Hospital. https://orcid.org/0009-0007-7942-1420

*For correspondence
Abstract
Pulmonary sclerosing pneumocytoma (SP) is a rare benign tumor of the lung that may histologically resemble malignant neoplasms, particularly during frozen section evaluation. We report a case of a 19-year-old female with an incidentally detected pulmonary nodule. Intraoperative frozen section examination raised suspicion of malignancy, leading to lobectomy. However, permanent histopathological evaluation revealed the characteristic dual cell population arranged in papillary, sclerotic, and hemorrhagic patterns. Immunohistochemistry confirmed the diagnosis of SP, demonstrating positivity for EMA and TTF-1 in both tumor cell types, while Napsin-A and cytokeratin were positive only in surface epithelial cells. The round stromal cells showed weak estrogen receptor expression, and the Ki-67 proliferation index was low. Recognition of the histological spectrum and immunophenotype of SP is essential to avoid misinterpretation and unnecessary extensive surgical procedures.
[Journal of Histopathology and Cytopathology, 2026 Jul; 10 (2):163-169]
DOI: https://www.doi.org/10.69950/jhc.2026.10.2.12

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jhc2026v10i2s11

Case Report
Heterotopic Ossification of the Gallbladder Associated with Chronic Cholecystitis: A Case Report
*Anjum R,1 Hossain  GZ2

  1. *Dr. Rahat Anjum, Associate Consultant, Histopathology & Cytopathology, Apollo Imperial Hospitals, Zakir Hossain Road, Chittagong r.dr@gmail.com. ORCID: https://orcid.org/0009-0005-2233-6992
  2. Dr. GM Zakir Hossain, Professor, Department of Urology, Chittagong Medical College Hospital. ORCID: https://orcid.org/ 0009-0004-5050-6058

*For correspondence
Abstract
Hetrotopic ossification  in the gall bladder is a rare condition, with  few reported cases. Its pathogenesis remains unclear, though chronic  inflammation may predispose to the condition. An  18 yr old girl underwent laparoscopic cholecystectomy due to persistent upper quadrant pain, nausea and postprandial vomiting. Preoperative ultrasound revealed a polyp with features  of  cholecystitis. The post operative course was uneventful.  Histopathological examination showed fibromuscular hyperplasia, infiltration of chronic inflammatory cells, including foamy histiocytes in the lamina propria. Rokitansky–Aschoff sinuses were present. The polypoid area exhibited denuded epithelium, mature bone formation and marrow elements without evidence of metaplasia,  dysplasia or malignancy.
[Journal of Histopathology and Cytopathology, 2026 Jul; 10 (2):160-162]
DOI: https://www.doi.org/10.69950/jhc.2026.10.2.11
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