Tag: FNAC

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jhc2025v9i1s7

Original

Computed Tomography Guided Fine Needle Aspiration Cytology of Mass Lesions of Lung: A Study of 56 Cases

*Wahed A,1 Islam N,2 Hossain MM,3 Nurunnabi M4

 

  1. *Dr. Abdul Wahed, Lecturer, Department of Pathology, Tangail Medical College, Tangail 1900, Bangladesh. shouravsomc88@gmail.com, ORCID: https://orcid.org/0009-0004-6273-0145
  2. Nazmul Islam, Associate Professor, Department of Pathology, Army Medical College Cumilla, Cumilla 3500, Bangladesh. nazmul47@gmail.com
  3. Mohammad Mosharaf Hossain, Assistant Professor, Department of Medicine, Tangail Medical College, Tangail 1900, Bangladesh. mosharaf51@gmail.com
  4. Mohammad Nurunnabi, Assistant Professor, Department of Community Medicine and Public Health, Sylhet Women’s Medical College, Sylhet 3100, Bangladesh. nur.somch@gmail.com

 

*For correspondence

Abstract

Background: Fine needle aspiration cytology (FNAC) determines the type of tumour and affirms the diagnosis. Computed tomography (CT)-guided FNAC of suspicious lung masses is a widely employed, inexpensive diagnostic procedure.

Objective: To evaluate the age, sex, topographic distribution, size, and cytopathological diagnosis of lung mass lesions using CT-guided FNAC.

Methods: This descriptive cross-sectional study included 56 individuals with pulmonary mass lesions, most of which were presumably caused by neoplastic disease, as evidenced by chest radiographs and CT scans. The study was conducted between June 2022 and June 2024.

Results: The mean age of the study participants was 63.6±11.8 years, with more than half (51.8%) falling within the 46–65 age group. Lesions were more commonly found in the right lung (57.1%) compared to the left lung (42.9%). The upper lobe accounted for about two-thirds of the lesions (64.3%), while the middle lobe had the fewest (3.6%). Of all cases, 87.5% were malignant, and 12.5% were benign. The most common malignant lesions were squamous cell carcinoma (33.9%), adenocarcinoma (28.6%), and poorly differentiated carcinomas (21.4%). Small cell carcinoma was identified in 3.6% of cases. There was a statistically significant association between age group and type of malignancy (P<0.05), with the 46–65 age group showing a higher prevalence of malignant lesions (55.1%).

Conclusion: CT-guided FNAC is a highly effective and comparatively accurate diagnostic technique for pulmonary mass lesions, with a permissible complication risk.

[Journal of Histopathology and Cytopathology, 2025 Jan; 9 (1):48-54]

DOI: https://www.doi.org/10.69950/jhc2025v9i1s7

 

Keywords: FNAC, CT-guided FNAC, pulmonary mass lesions, Tangail, Bangladesh.

 

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JHC 2023 January v7 i1 s4

Original Contribution

Role of FNAC and Core Needle Biopsy in the Diagnosis of Breast Lesions

1.*Dr. Anindita Sarkar, MD (Pathology), Assistant Professor (C.C), Pathology Department, Rajshahi Medical
College. abantica.16@gmail.com.
2. Prof. Dr. S. M. Asafudullah, MD (Pathology), Professor and Head of Department of Pathology, Rajshahi Medical
College.
3. Dr. Khadiza Khanam, MD (Pathology), Professor, Pathology Department, Rajshahi Medical College.
4. Dr. Rukhshana Akhter Jahan, MD (Pathology), Associate Professor, Pathology Department, Rajshahi Medical
College.
5. Dr. Tanshina Afrin, MD (Pathology), Assistant Professor (C.C), Pathology Department, Rajshahi Medical College.
6. Dr. Rebeka Sultana, MD (Pathology), Consultant, Islami Bank Hospital, Rajshahi.
*For correspondence

Abstract
Background: Though excision biopsy of breast lump is considered to be the gold standard method
for diagnosis, there should be an improved and definitive method for establishing an accurate
diagnosis of breast lesions prior to surgery. This study was carried out to evaluate the efficacy and
diagnostic performance of fine needle aspiration cytology (FNAC) and core needle biopsy (CNB)
in the preoperative assessment of breast lesions.
Methods: This cross-sectional study was conducted in the private diagnostic center in Rajshahi,
Bangladesh over a period of one year from January 2022 to December 2022.A total of 60 cases
were subjected to both FNAC and CNB from the same breast lesions included in this study.
Result: The age range of total 60 patients was 22-85 years with mean age of 42.18 ±SD 12.15
years. 38 patients had benign lesions and 22 had malignant tumors. Sensitivity, specificity, positive
predictive value, negative predictive value, and diagnostic accuracy for FNAC were 89.4%, 100%,
100%, 84.6%, and 93.3%, respectively in diagnosing carcinoma. CNB had sensitivity, specificity,
positive predictive value, negative predictive value, and diagnostic accuracy of 94.7%, 100%,
100%, 91.6% and 91.6% respectively. Both FNAC and CNB showed statistically significant
association.
Conclusion: Taking into account the benefits and outcomes, combined approach of FNAC and
CNB can provide accurate preoperative diagnosis of breast lesions and provide important
information for appropriate treatment

[Journal of Histopathology and Cytopathology, 2023 Jan; 7 (1):21-26]
Keywords: FNAC, Core needle biopsy (CNB), Breast lesion

Full article

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jhc-2023-jan-v7-n1

Journal of Histopathology and Cytopathology

Official Organ of Bangladesh Academy of Pathology

Vol 7, No 1, January 2023
Cover front PDF
Index or Contents PDF
Contacts, Price …

Contents

 
Editorial
1. PD-L1 Expression in Colon Carcinoma: A Promising Target for Immunotherapy
Mimi SA
Original Contributions
2. Immunohistochemical Evaluation of Ki67 Expression in Premalignant and Malignant Esophageal Lesions – Study of 54 Cases in a Tertiary Care Hospital
Sultana S, Afrin SS, Khan ZB, Zabin SG, Sweety RA, Islam MA,Shaheen N, Jahra FT, Jeba R, Dewan RK
3. Histopathological Analysis of Uterine Lesions in Hysterectomy Specimen at a Tertiary Hospital
Hossain MS, Sultana SS, Hossain SA
4. Role of FNAC and Core Needle Biopsy in the Diagnosis of Breast Lesions
Sarkar A, Asafudullah SM, Khanam K, Jahan RA, Afrin T, Sultana R
5. Evaluation of Stromal CD10 Expression and its Correlation with other Clinicopathological Factors in Invasive Breast Carcinoma
Imrana F, Mamun MS, Hossain SM, Hassan A
6. Stromal Expression of CD10 in invasive Ductal Carcinoma and its Relationship with ER, PR and HER2-neu Status

Imrana F, Mamun MS, Hossain SM, Hassan A
Case Reports
7. Cauda Equina Neuroendocrine Tumor – A Case Report
Shams S, Islam MN
8. Information for contributors
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