Category: Journal

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JHC 2023 July v7 i2 s3

Original Contribution

Histomorphological Patterns of Different Breast Lesions in a Tertiary Care Hospital

1. *Dr. Tanshina Afrin, MD (Pathology), Assistant Professor (C.C), Pathology Department, Rajshahi Medical
College. tanshinaafrin@gmail.com
2. Prof. Dr. S M Asafudullah, Professor and Head of Department of Pathology, Rajshahi Medical College
3. Dr. Khadiza Khanam, Professor, Pathology Department, Rajshahi Medical College.
4. Dr. Arefa Sultana, Associate Professor, Pathology Department, Rajshahi Medical College.
5. Dr. Anindita Sarkar, Assistant Professor (C.C), Pathology Department, Rajshahi Medical College.
6. Dr. Nazifa Islam, Assistant Professor (C.C), Pathology Department, Rajshahi Medical College.
7. Dr. Samrose Sultana, Assistant Professor (C.C) Pathology Department, Rajshahi Medical College.
* For correspondence

Abstract
Objective: Breast lesions are heterogeneous diseases that consist of several distinct entities
with remarkably different characteristic features. The present study was conducted to assess
histopathological findings of breast lesions in excision biopsy samples.
Methods: This cross-sectional study was conducted in the Department of Pathology, Rajshahi
Medical College over a period of one year from July 2021 to June 2022. A total of 105 cases of
breast lesions were included in this study.
Result: Out of 105 cases of breast lesions studied, 59 cases (72%) were malignant and 46 cases
were benign lesions. Fibroadenoma (18 cases out of 46) was the most common benign lesion
followed by breast abscess (9 cases out of 46). On the other hand, invasive ductal carcinoma
was the highest occurred malignant tumour (59 cases, 56%). The age range of breast lesion was
15 to 75 yrs and highest incidence was in between 31-50 years (both benign and malignant).
Most of the breast lesions were occurred in left breast (62%).
Conclusion: Histopathological examination plays an important role in differentiating between
benign and malignant lesions. In the present study the most common benign breast lesion was
fibroadenoma and the most common malignant lesion was infiltrating ductal carcinoma. The

[Journal of Histopathology and Cytopathology, 2023 Jul; 7 (2):62-68]
Keywords: Histopathology, Malignant, Benign lesions, Breast lesion

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JHC 2023 v7 i2 s2

Original Contribution

Ultrasound Guided Fine Needle Aspiration Cytology of Lung
Lesions

1. *Dr. Rukhshana Akhter Jahan, Associate Professor, Department of Pathology, Rajshahi Medical College,
Rajshahi. jahanrukhshana@gmail.com
2. Professor Dr. S M Asafudullah, Professor & Head, Department of Pathology, Rajshahi Medical College,
Rajshahi. drshamol@gmail.com
3. Dr. Rebeka Sultana, Consultant Pathologist, Raj Pathology, Rajshahi. doctorrebekasultana@gmail.com
4. Dr. S. M. Moshaddeq Hossain, Assistant Professor, Department of Pathology, Rajshahi Medical College,
Rajshahi. mridulrmcbd@yahoo.com
5. Dr. Samrose Sultana, Assistant Professor, Department of Pathology, Pabna Medical College, Pabna.
samrosesina@gmail.com

Abstract
Background: This study was aimed to evaluate the role of transthoracic ultrasound guided
FNAC in diagnosis of peripheral lung lesion. It is an important and useful investigation to
differentiate between benign and malignant lesions of lung. USG guided FNAC of lung lesion
is a safe, radiation free, and cost effective method. Besides, the procedure is simple and
complications if occur, can be managed conservatively.
Methods: This was a cross-sectional study conducted at the department of Pathology,
Rajshahi Medical College. Some samples were also collected from a private diagnostic centre,
Rajshahi over a period of one year from January 2021 to December 2021. 150 patients who
fulfilled inclusion criteria were included in this study. After properly explaining the procedure
and taking informed consent, USG guided FNAC was done in all the patients. Radiological
and cytological data of enrolled patients was collected prospectively and analyzed.
Results: Among the 150 patients, this study comprising of 120 male and 30 female in age
range of 21 to 90 years. Malignancy was the most common cytological diagnosis (76%) while
as benign diagnosis was reached in 22.66%. In 1.33% of patients, FNAC was inconclusive.
Squamous cell carcinoma was the most common malignancy diagnosed in 46(30.66%)
patients, followed by adonocarcinoma 31(20.66%), 19(12.66%) patients had undifferentiated
carcinoma, metastatic carcinoma 09(06%), small cell carcinoma 07(4.66%), and Non Hodgkin
lymphoma was diagnosed in 02(1.33%) patients. Among the benign group, nonspecific
chronic inflammation was diagnosed in 18(18%) patients, tuberculous granuloma 07(4.66%),
while the smear was inconclusive in 02(1.33%) patients.
Conclusion: Ultrasound guided fine needle aspiration cytology is safe, less expensive, less
time consuming, less invasive diagnostic tool with high degree of accuracy and no radiation
toxicity to lung lesions

[Journal of Histopathology and Cytopathology, 2023 Jul; 7 (2):55-61]
Keywords: Malignancy, Tuberculosis, USG guided Fine needle aspiration cytology.

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JHC 2023 July v7 i2 s1

Editorial

Challenges and Prospects of Establishing a Genome Sequencing Laboratory in Bangladesh

Dr. DM Arifur Rahman
Associate Professor (Histopathology), TMSS Medical College, Bogura. arifurrahmandm@gmail.com
Abstract: Not available
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